Provoked gastro‐oesophageal reflux?

Metoclopramide in gastrooesophageal reflux.

In 30 patients with gastrooesophageal reflux, intravenous metoclopramide (Maxolon) has been shown to increase the gastrooesophageal sphincter pressure. The rise is dose-related until a maximum pressure, proportional to the resting sphincter tone, is reached. The effect is reversed by atropine. Peristaltic waves are increased in pressure by metoclopramide.In 18 patients with gastrooesophageal re...

Surgery for uncomplicated gastrooesophageal reflux.

Effect of intravenous metoclopramide on gastrooesophageal reflux.

The effect of intravenous metoclopramide was studied radiologically in 40 patients with gastrooesophageal reflux. In no patient was reflux significantly diminished.

Three year follow up of patients with gastrooesophageal reflux disease.

Data on the natural course of gastrooesophageal reflux disease are sparse. One hundred and sixty six patients with typical reflux symptoms (heartburn and/or acid regurgitation) and pathologic pH monitoring (reflux time > 8.2% upright and/or > 3.0% supine) were studied. The patients were followed up by questionnaire and interview for a mean of 41 (seven to 86) months after diagnosis of reflux di...

Severe Gastrooesophageal Reflux Disease Associated with Foetal Alcohol Syndrome

Prenatal alcohol exposure may have adverse effects on the developing foetus resulting in significant growth restriction, characteristic craniofacial features, and central nervous system dysfunction. The toxic effects of alcohol on the developing brain are well recognised. However, little is known about the effects of alcohol on the developing gastrointestinal tract or their mechanism. There are...